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Neurodegenerative diseases Mitochondrial dysfunction in Alzheimers disease (AD) includes mitochondrial dynamic changes, a decrease in ATP generation, increased oxidative stress, mitophagy damage and mtDNA mutation

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Moreover, our results highlight the essential role of vitamin B12 in homocysteine metabolism, as supplementation was associated with a significant reduction in serum homocysteine levelsan important biomarker associated with cardiovascular and neurodegenerative diseases