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Histological examination of intestinal segments revealed remarkable differences between LTF-pretreated endotoxemic mice and LPS counterpart

Activation of the NLRP3 inflammasome increased ROS generation with a loss of mitochondrial membrane potential and mitochondrial integrity in human microglial cells, independent of virus replication

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NMN and NR are NAD precursors, smaller molecules the body converts into NAD+ through the salvage pathway

Cells were washed twice with PBS and then placed in a fluorescence-compatible plate reader and fluorescence measured (reduced Ex:475 nm/Em:580640 nm, oxidized Ex:475 nm/Em:500550 nm)