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Safety Profile and Tolerability Cagrilintide demonstrates a favorable safety profile consistent with other peptide-based metabolic therapies

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Biomaterials 165, 1424

Studies regarding cytotoxicity are rare compared to the numerous reports describing antimicrobial activities

408 Studies have shown that the loss of GLP-1R in astrocytes can impair mitochondrial integrity, leading to the dysfunction and inhibition of glucose uptake and -oxidation