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Following dichotomization of ALT responders based on a median 12.9% decrease from baseline, we found that ALT responders were younger in age and did not have severe diabetes compared with ALT non-responders

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15,89,90 The second category involves synaptic proteins, including cell adhesion, scaffolding, and signalling molecules, which can affect synapse structure and function during different processes of synapse formation, elimination, transmission, and plasticity