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Charcoal rot is a high priority fungal disease in sorghum [ Sorghum bicolor (L.) Moench], causing tremendous crop losses where ever sorghum is grown (Tarr, 1962, Tesso et al ., 2012)

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Importantly, TNF type 1 receptor knockout mice are resistant to the initiation and progression of NAFLD in response to both high-carbohydrate and methionine- and choline-deficient diets 26,27