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Cysteine residues within polypeptide chains can undergo oxidation to form disulfide bridges (-S-S-), thereby stabilizing protein tertiary and quaternary structures

To further investigate these findings, we determined whether the mutants exhibited an increased response to novelty

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Ultimately, these data should inform biomarker-enriched, early-phase clinical trials that co-stratify patients by pathway activity and genomic alterations, thereby accelerating the development of precision therapies for women with EAOC

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Treatment: Moisturizers, oral/topical medications, lifestyle changes