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Based on these studies, it may be concluded that -synuclein is responsible for both the diminished activity of catalase and the increased formation of hydrogen peroxide, as substantiated by the increased oxidative stress markers in Parkinsons disease

doi: 10.1186/1477-5956-11-20 86 KimSJParkJHKimKHLeeWRKimKSParkKK

FIGURE 2 Particle size and surface properties are key determinants of MPs neurotoxicity

Li J, Cao F, Yin H-l, Huang Z-j, Lin Z-t, Mao N, et al