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The researchers discovered that both patient cohorts exhibited significant signs of elevated oxidative stress and consequent mitochondrial damage

Thyroid 25(2):145146

C677T polymorphism in the MTHFR gene (A222V, rs1801133) is associated with a decrease in enzymatic activity to 3570% in homozygotes

This study was supported by the Yunnan Provincial Science and Technology Department Science and Technology Plan Project (202101AZ010001-015), the Yunnan Province Xingdian Talent Support Program Distinguished Physician Special Project (YNWR-MY-2020-084), the Master of Traditional Chinese Medicine Zhang Zhen Studio Project of the Second Affiliated Hospital of Yunnan University of Chinese Medicine (2022YZEYZG001), the Yunnan Provincial Joint Special Project on Traditional Chinese Medicine - Youth Program (202401AZ070001-114), and the Specialty Development Project of the Second Affiliated Hospital of Yunnan University of Chinese Medicine (202105AE160018)

Although the mechanism of infection has been intensively studied, the fine regulation of the interaction between bacteria and the host immune system remains to be revealed

Concentrations in published research range from 0.05% to 1%, depending on the target tissue and intended outcome