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Phase 1/2 open-label dose-escalation study of plasmid DNA expressing two isoforms of hepatocyte growth factor in patients with painful diabetic peripheral neuropathy

Finally, medicinal chemistry should advance analogs with improved stability and minimized promiscuous protein binding, specifically aiming to reduce marrow suppression and mitochondrial liabilities while retaining on-lesion potency (103)

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Acetyl-L-Carnitine, N-acetylcysteine, and Inositol in the Treatment of Psychiatric and Neuropsychiatric Disorders

MOTS-c is generally considered better for anti-aging purposes because it directly targets mitochondrial function and metabolic decline, both of which are central to the aging process

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