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coli L-asparaginase involved the addition of polyethylene glycol group into the native enzyme that can reduce immunogenicity and prolonged half-life (1.24 day for native and 5.73 days for pegylated formulation) [100]
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The development of the nervous system in progeny may be influenced epigenetically by molecules associated with one-carbon metabolism, such as betaine, choline, and folate (Ars et al., 2019)
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Arora, K., J.M
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