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reported that as the disease progresses, DM increases the risk of CD two-fold, including effects on learning, memory, and spatial cognitive abilities in humans (Wang et al., 2022a)

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In particular, the mitochondrial SOD (MnSOD/SOD2) converts .O 2 . into H 2 O 2 , which is less reactive than .O 2 . and so can readily be used for cellular signalling

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