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The same protein, with an additional enzymatic activity, then catalyzes the introduction of cysteine at the C- 2 position of the imidazole ring in hercynine, forming cysteinyl hercynylsulfoxide

Beyond direct metabolic effects, BAs indirectly influence insulin sensitivity and systemic metabolic homeostasis by modulating the gut microbiota composition and promoting the production of microbial metabolites such as short-chain fatty acids (SCFAs) [76, 77]

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C., Jr., Rassart, ., & Desrosiers, R

Nevertheless, these strategies are proving to be limited efficacy because of ineffective vascularization, neuropathy, compromised immunity and inflammation that persists at the wound site