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Increased peroxidation in CKD due to oxidative stress can lead to a profound modification of cellular structures and function, impairing erythrocytes

Valosin-Containing Protein P97/P47 Complex-Interacting Protein 1 (VCIP135) binds and stabilizes MAT2A in response to folate signaling in HCC and promotes tumor formation and progression in DEN/high-fat diet (HFD)induced HCC mouse models (Fig

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Erianin effectively inhibits the proliferation of cisplatin-resistant cells by regulating the Wnt3/-catenin signaling pathway (16,17), which provides a novel possibility for overcoming common clinical chemotherapy resistance

Each hepatocyte appeared polyhedral with acidophilic granular cytoplasm

Overall, our findings establish hyperactive polyadenylation as a core oncogenic mechanism linking RNA processing to cancer metabolism in AML, highlighting the PAPOLAGSTM2HNEDLD axis as a promising therapeutic target