To improve muscular efficiency and endurance during training
So it can take 2-5 years before you see signs of B12 deficiency
[131] [132] Species from the following genera and the following individual species are known to synthesize B 12 : Propionibacterium shermanii , Pseudomonas denitrificans , Streptomyces griseus , Acetobacterium , Aerobacter , Agrobacterium , Alcaligenes , Azotobacter , Bacillus , Clostridium , Corynebacterium , Flavobacterium , Lactobacillus , Micromonospora , Mycobacterium , Nocardia , Proteus , Rhizobium , Salmonella , Serratia , Streptococcus and Xanthomonas
This elevation in NAD+ levels activates critical metabolic pathways including SIRT1 (sirtuin 1), a longevity-associated protein that regulates insulin sensitivity, mitochondrial function, and cellular stress resistance
This monitoring serves both to detect any unexpected effects and to document individual response patterns
We also recognize that the evidence is less conclusive for individuals with normal B12 levels