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Three consecutive prolines at positions 35 (Pro-Pro-Pro) and an additional proline at position 8 create local conformational rigidity through the unique angle constraints of pyrrolidine-containing residues

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Tacrolimus 0.1% ointment showed effectiveness over a 1-year period in children with AD, while another open-label trial revealed efficacy in adult patients with AD

Youve seen it in hospitals for dehydration or medications

A: For topical use, clinical studies suggest 0.5-1.0 mg/mL applied twice daily

That protects the hair follicles from damage caused by oxidative stress