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4.2 Gut microbiota dysbiosis and abnormal activation of complement C4 Genetic susceptibility to schizophrenia is significantly associated with polymorphisms in genes related to the complement system, largely attributable to alleles of the complement C4 gene located within the major histocompatibility complex region on chromosome 6 (132)

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For acute flares of gout, it is key to treat as quickly as possible and choosing a medication least likely to cause side effects, with special attention to individual comorbidities

For instance, Fan et al

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