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The intrinsic factors include neurotrophic factors [7], transcriptional programs [8], inflammatory cytokines [9], neurotransmitters and hormones [10]

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Research uses 200 to 800 mcg per day, with 10 mcg/kg as the common animal reference, which scales to roughly 200 to 500 mcg/day in humans

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Upon densitometric analysis, it was found that after an initial 2 fold decrease in gene expression (Table 4) in response to nitrogen starvation, gene transcription appeared to be up-regulated after 2 hrs (approximately 2 fold, Table 4) exposure to these conditions