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Specifically, the uncontrolled release of pro-inflammatory cytokines such as IL-1, IL-6, and TNF- leads to myocardial depression, endothelial dysfunction, and triggers apoptosis pathways in cardiac cells 51

Biochem Biophys Res Commun 482(3):419425

PRPs Role in Cartilage Preservation and Disease Modification Unlike traditional treatments that primarily suppress symptoms , PRP has shown potential to slow OA progression and enhance cartilage repair : A study using MRI imaging found that patients receiving PRP had higher cartilage thickness and lower cartilage degeneration scores compared to those receiving HA (PMID: 35188121)

Inhibitory effect of luteolin on estrogen biosynthesis in human ovarian granulosa cells by suppression of aromatase (CYP19) J

From the eight studies that showed PUFAs beneficial effects on depression, we observed that the range of the total daily dosage of the EPA ranged from 0.7 g to 2 g and DHA was from 0.4 g to 0.8 g