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Microglia are transformed into DAM by recognizing Neurodegeneration-Associated Molecular Pattern (NAMP) danger signals which leak from damaged neuronal cells in analogy to the peripheral immune systems pathogen- and damage-associated stress signals (PAMPs and DAMPs) 23

This is a very different model than were used to

April 15, 2026

The exacerbation of white matter integrity is linked to poor sensorimotor performance

The peptide activates TGF-beta and VEGF signaling pathways, stimulating fibroblast proliferation, collagen I/III synthesis, and glycosaminoglycan production

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