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"Biological activities of selected peptides: skin penetration ability of copper complexes with peptides." Journal of Cosmetic Science

doi:10.23750/abm.v90i3-S.8159 3Holland KE, Soung PJ

Melanin is the pigment present in the skin and its inhibition produces a skin lightening effect

Because GHK-Cu can penetrate the skin barrier effectively, it is used in various skincare products to promote a youthful complexion

In some instances, the addition of a thickening agent and a pH of formulation or compositions as described herein, allows for sterilization of a formulation described herein without any substantial degradation of the therapeutic agent in the otic formulation or composition

10.1007/s10620-007-0193-7 226 WreeA.EguchiA.McgeoughM