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These results highlight the need for clinical trials to determine effective dosing, treatment duration, combination strategies, and long-term safety

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As understanding of growth factor signalling pathways expanded, follistatin variants such as Follistatin-344 began to be studied in experimental cellular models investigating regulatory protein interactions

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Folic acid, which is the form found in fortified foods and supplements is also a poor substrate for folylpolyglutamate synthase accounting for its efficient uptake from the intestines and release to the blood