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Studies on athletes show whole-body cryotherapy reduces circulating levels of the pro-inflammatory cytokine IL-1 beta while increasing the anti-inflammatory cytokine IL-10 and the cytokine inhibitor IL-1 receptor antagonist (IL-1ra)

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Sin embargo, las mujeres mayores de 65 aos pueden requerir reducciones de dosis del 25-30% debido a tasas de eliminacin alteradas y mayor sensibilidad a terapias con pptidos

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