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To neutralize ROS, systematic biological detoxification processes are used to maintain their normal level

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Supplementation with 300-600 mg/day has been shown to increase intracellular glutathione levels by 30-70% in cell culture and animal studies, with more modest increases in human trials (Suh et al., Proc Natl Acad Sci, 2004) [25]

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Parenteral administration should always follow proper aseptic technique, and the solution should be inspected for particulates or discoloration before use

Redox-sensitive GFP (roGFP) allows a direct read-out of the glutathione redox potential ( E GSH ) particularly in reducing compartments (Meyer and Dick, 2010)