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High concentrations of glutamate are known to induce ROS formation by certain enzymes, for example, xanthine oxidase, resulting in oxidative damage

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Is the complete WAGGDASGE sequence stated

10.1016/j.cell.2016.02.014 43 JangY.-Y.SharkisS

Co-activation of AKT and c-Met triggers rapid hepatocellular carcinoma development via the mTORC1/FASN pathway in mice

Mitochondrial biogenesis is only advantageous if mitochondria are functional We examined mitochondrial staining by TOM20 immunohistochemistry in HCT116 xenografts and AKP orthotopic tumours treated with 5FU and/or metformin