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These results suggest potential benefit for selenium supplementation in order to enhance antioxidant defenses in female patients with PCOS ( Selenium is critical in the synthesis and metabolism of thyroid hormones

Cytosolic Ca2+ regulates the energization of isolated brain mitochondria by formation of pyruvate through the malate-aspartate shuttle

As traditional cases of SJS/TEN do not manifest initially with a rash, but a flu-like prodrome, and do not present in a photodistributed pattern, this is evidence that UVR precipitates the disease process, altering its course and clinical presentation

Mitochondrial staining and reactive oxygen species (ROS) detection For mitochondrial staining, after washing once with PBS, 5 mM MitoTracker (Thermo Fisher Scientific) and 200 mM Hoechst (Thermo Fisher Scientific) were added to the cells