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Nevertheless, current GSH-activated prodrugs frequently face challenges in achieving selective activation within heterogeneous tumor microenvironments

Almost 90% of cellular GSH resides in the cytosol, with roughly 10% found in the mitochondria and a small fraction in the endoplasmic reticulum

Differential diagnoses to consider Septic arthritis should be considered in patients with monoarticular joint pain, with erythema, warmth and joint immobility

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