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Immunohistochemical analysis showed that levels of TNF- , IL-1, and lactate dehydrogenase (LD) were reduced in the curcumol treated mice group (Wu K
In general, these hypotheses present the assumption that microbiota of proper composition regulates epithelial barrier function, including by regulating barrier permeability and TJ, influencing vascular permeability and angiogenesis, and affecting local inflammation and GALT tolerance [1, 55, 56]
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BPC-157 demonstrates both local and systemic effects, meaning even injections at some distance from the injury site provide benefit, though local administration may optimize outcomes
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