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It is well established that the ovarian factorthe decline in oocyte quantity and quality, which occurs because of an increase in meiotic errors in this finite poolbecomes a more important consideration with age (Johnson et al., 2004), most current evidence points to the existence in human ovaries of a more or less finite, non-renewable, pool of oocytes which is gradually depleted until menopause

It can therefore be predicted that the water that is produced will be deupleted, for two reasons

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