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Although compounds such as vitamins, polyphenols, and plant-derived molecules have demonstrated promise in preliminary studies, more comprehensive clinical trials are needed to confirm their therapeutic value, determine optimal dosages, and assess long-term safety

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[DOI] [PubMed] [Google Scholar] 268.Tew KD

In addition, the mRNA expression of neurotrophins such as BDNF, NGF, NT-3, and NT-4/5 was significantly decreased after the treatment with CRE in 12Z cells

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