61,62,63 CDO is highly regulated at the level of protein turnover, as oxidative degradation of cysteine by CDO is highly inducible, 64 and high cysteine levels inhibit CDO ubiquitinylation and reduce its proteasomal degradation
Estrogen regulation of growth hormone action
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Transfection with hsa-let-7c low-expression virus brought about the upregulation of IGF-1R and the enhanced odonto/osteogenic differentiation in IGF-1-treated SCAPs, as indicated by the upregulation of several odonto/osteogenic markers ( DMP1 /DMP1, COL-I /COL-I, ALP, RUNX2 /RUNX2, OSX /OSX, DSPP /DSP and OCN /OCN) in vitro
Plant J 11(6):11871194