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The augmentation of antioxidant reserves, by elevating GSH levels, also resulted in a significant reduction in the accumulation of oxidative DNA damage implicated in the pathophysiology of diabetic complications

Thus, additional models are necessary to validate findings from rodent models in humans

While human clinical data is limited, years of anecdotal use and animal studies have helped shape reliable dosing practices

There is currently insufficient clinical research to confirm the safety of IV glutathione during pregnancy or breastfeeding

The smaller airways lead down into the alveoli where gas exchange occurs and where surfactants are increasingly required to prevent airway collapse during exhalation (Possmay et al., 2001)

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