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Although the exact mechanism is unknown, the lung microbiome has an impact on lung development

Understanding and addressing irAEs is a pressing issue for another reason as well: given that only about a third of cancer patients respond to immune checkpoint inhibitors, research labs and pharmaceutical companies are doubling down on efforts to expand the efficacy to more patients, and one of the approaches is to combine different immunotherapeutics to target different pathways

Patients notice a difference in about 1-2 weeks, but 4 weeks is the recommended therapy duration

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The first one is to control nuclear receptors

Autotaxin promotes the degradation of the mucus layer by inhibiting autophagy in mouse colitis