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Beyond these predisposing differences in the genome, AUD is likely associated with dynamic alterations in gene expression and chromatin conformation, plausibly in brain regions associated with onset and maintenance of motivated and rewarding behaviors, stress responsivity and cognitive control

Because the nucleoprotein assembly realistically mimics the stability of the EBOV, the EBOV-TMV probe could be spiked into patient samples prior to processing and therefore function as an internal standard