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"We're on the cusp of something very big here and it's going to have quite a significant impact on public health."

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It's more like a series of important steps taken by different people years apart

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Non-invasive approaches include the detection of biological markers such as enzymes, antibodies, or specific proteins (e.g., lactoferrin, calprotectin, and C-reactive protein in bodily fluids that can be collected non-invasively, such as urine, fecal matter, or saliva (Lewis, 2011)