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Daily administration of two or more synaptogenic compounds simultaneously might overwhelm cellular synthetic capacity or trigger compensatory downregulation faster than either compound would alone, potentially favoring alternating administration schedules where different compounds are used on different days

JCI Insight 4:e130111 Mizzi N, Blundell R (2025) Glycine receptors: structure, function, and therapeutic implications

Baicalein inhibits RLS3-induced ferroptosis in melanocytes

245 According to clinical research, TRP and tryptophan catabolites (TRYCATs) may play a crucial role in psychiatric illnesses, including MDD

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Sies H (2017) Hydrogen peroxide as a central redox signaling molecule in physiological oxidative stress: Oxidative eustress