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doi: 10.1016/j.expneurol.2016.02.009 22 ButlerR.BatesG

Iron accumulation typifies renal cell carcinoma tumorigenesis but abates with pathological progression, sarcomatoid dedifferentiation, and metastasis

Carroll PV, Umpleby M, Alexander EL, Egel VA, Callison KV, Snksen PH, Russell-Jones DL

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Puthumana J, Kim B M, Jeong C B, Kim D H, Kang H M, Jung J H, Kim I C, Hwang U K and Lee J S 2017 Nine co-localized cytochrome P450 genes of the CYP2N, CYP2AD, and CYP2P gene families in the mangrove killifish Kryptolebias marmoratus genome: Identification and expression in response to B[]P, BPA, OP, and NP

This suggests that many reported candidate biomarkers were either highly dependent on technical considerations, or represent false positives due to unaccounted confounders