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doi: 10.1186/s12958-023-01159-6

Growth hormone (GH) is a 191-amino-acid protein hormone produced by the anterior pituitary gland

MK-677 and Oral Growth Hormone Secretagogues MK-677 (Ibutamoren) is a non-peptide GHS-R1a agonist that shares Ipamorelin's receptor target but is orally bioavailable

On one hand, activity at such vanishingly small concentrations is consistent with GHK-Cus proposed role as a physiological signaling molecule rather than a blunt pharmacological agent, which is genuinely intriguing

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Chronic inflammation increases white blood cells and platelets, damaging cells and microbiota, reducing organ function, and raising the risk of health issues