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Essentially, two groups can be distinguished: (i) molecules containing GSH or GSH-like moiety and (ii) molecules whose enzymatic activation occurs through a GSH-conjugate intermediate 109
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Early recognition of potential complications can prevent serious adverse outcomes
(Source 3) 7
Despite that mitochondria are exposed to the generation of oxidant species, the existence of an efficient antioxidant defense system, of which mGSH is a critical component, prevents or repairs oxidative damage generated during normal aerobic metabolism ( MITOCHONDRIAL ROS GENERATION AND DEFENSE Reactive oxygen species can be generated in several intracellular sites, including cytosol, peroxisomes, plasma membrane, and ER
